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Neuronox 200U | Purified Botulinum Toxin Type A Complex | Better Botox Injections | Same Product to Meditoxin

The First Choice of Botulinum Toxin Type A
Neuronox® is marketed under different brand names such as Botulift®, Siax®, Cunox®, and Meditoxin®

The minimum order quantity is 5pcs


Totally same result with Botox and Dysport
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$179.00
  • Buy 50 for $170.00 each and save 6%
  • Buy 100 for $165.00 each and save 8%

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Description

Details

Composition

Each vial contains

  • Active ingredient: Clostridium botulinum toxin type A 200 units(U) (Korean Minimum Requirement for Biopharmaceutical Product) 
  • Stabilizer: Human serum albumin 1.0mg (Korean Minimum Requirement for Biopharmaceutical Product) 
  • Isotonic agent: Sodium chloride (EP) 1.8mg

* One unit(U) of Neuronox corresponds to the calculated median intraperitoneal lethal dose (LD50) in mice.

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Description

It appears as a lyophilized white powder for injection in a colorless transparent vial.

Proven Efficacy & Safety

The efficacy and the safety of Neuronox are proved to be comparable to Botox(Allergan Inc.)’s in various clinical studies.

Glabellar Frown Lines

The comparative clinical study for glabellar frown lines1) with Neuronox vs. Botox: Comparable Efficacy and Safety.

Neuronox botox for frown lines

Methodology: Multicenter, double-blind, randomized, parallel design, active-controlled phase III clinical study. Each patient was randomly assigned to receive 20U (0.5ml) of either Neuronox(n=142) or Botox(n=146). The total dose was distributed over 5 injection points into corrugators and procerus. Results of the treatment were evaluated at 4-week intervals: up to 16 weeks.

Subjects: 314 healthy adult patients (aged between 20 to 65) with moderate or severe glabellar lines at maximum frown. *four-point scale (0=none, 1=mild, 2=moderate, 3=severe)

Results: Neuronox was proved its non-inferiority to Botox in this clinical study. Therefore, Neuronox is effective and safe for the treatment of glabellar frown lines.

SAFETY

In this study, 26.92% of patients treated with Neuronox and 22.29% of patients received Botox experienced adverse events. There was no statistical difference in the incidence and the severity of adverse events between two products (p=0.3416).

The comparative clinical study for glabellar frown lines with Neuronox vs. Botox: More satisfaction

Neuronox result

Essential Blepharospasm

The comparative clinical study for essential blepharospasm with Neuronox vs. Botox: Comparable Efficacy and Safety

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Methodology: Multi-center, double-blinded, randomized, active-controlled, parallel designed, phase Ⅲ clinical study.

Subjects: 60 patients diagnosed as essential blepharospasm (Neuronox n=31 / Botox n=29).

Results: The efficacy of Neuronox was not inferior to Botox in this clinical study. No difference was noted in the frequency of adverse event.
Neuronox can be safely used as an alternative to Botox treatment at 1:1 equivalence.

Equinus Deformity in Cerebral Palsy

The comparative clinical study for equinus deformity in cerebral palsy with Neuronox vs. Botox: Comparable Efficacy and Safety

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Methodology: Multi-center double-blinded, randomized, active-controlled, parallel designed, phase Ⅲ clinical study

Subjects: 119 pediatric patients diagnosed as spastic cerebral palsy with equinus foot deformity (Neuronox n=60 / Botox n=59)

Results: Neuronox was not inferior to Botox in this clinical study. No differences were noted in the frequency of adverse event.
Neuronox can be safely used as an alternative to Botox treatment.

Indication and Usage

1. Neuronox is indicated for the treatment of benign essential blepharospasm in patients 18 years of age and above.

2. Neuronox is indicated for the treatment of equinus foot deformity due to spasticity in pediatric cerebral palsy patients 2 years of age and above.

3. Neuronox is indicated for the treatment of temporarily improve moderate to severe glabellar wrinkles related to eyebrow wrinkle muscle (corrugator muscle) and/or procerus muscle activity in adults aged from 20 to 65.

4. Neuronox is indicated for the treatment of Muscle spasticity: upper limb local muscle spasticity related to stroke in adults aged 20 or more

Storage

The unopened lyophilized vial should be stored in a freezer(blow -5℃) or refrigerator (2~8℃).

How supplied

Neuronox is supplied in a single-use vial.

Expiration

The shelf-life of Neuronox is 36 months from the manufacturing date.

Specification

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