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Description
Details
Composition
Each vial contains
- Active ingredient: Clostridium botulinum toxin type A 300 units(U) (Korean Minimum Requirement for Biopharmaceutical Product)
- Stabilizer: Human serum albumin 1.0mg (Korean Minimum Requirement for Biopharmaceutical Product)
- Isotonic agent: Sodium chloride (USP) 1.8mg
* One unit(U) of Botulax corresponds to the calculated median intraperitoneal lethal dose (LD50) in mice.
Description
It appears as a lyophilized white powder for injection in a colorless and transparent vial. It should become colorless transparent liquid when dissolved in the diluent (physiological saline solution).
Why Choose Botulax?
Botulax is botulinum toxin product with high purity which was developed with patented manufacturing technique.
Quality & Stability
Botulax keeps stabilized potency in each product followed by strict quality control.
Botulax shows stable potency on the condition of cold storage of freezer after reconstitution.
Essential Blepharospasm
This clinical study was conducted to evaluate the safety and efficacy of Botulax compared to other botulinum toxin type A product (Botox from Allergan, USA) in essential blepharospasm.
Methodology: A double-blinded, randomized assignment, active drug comparative, multi-center, Phase III clinical study.
Subjects: 225 patients diagnosed with essential blepharospasm and grade 2 to 4 spasms (Scott Method)
Results: Botulax showed non-inferior efficacy and duration to comparator drug. No serious adverse drug reaction.
Reconstitution and Dilution Technique
- Using an appropriate syringe, draw nonpreserved sterile saline (see dilution table below). 0.9% Sodium Chloride is the recommended diluent.
- Insert the needle and slowly inject the saline into the NABOTA vial in which vacuum is present.
- Inject slowly and avoid forming bubbles.
- Gently mix lyophilized NABOTA until it is completely clear and no particles are visible.
- Record the date and time of reconstitution. The solution should be administered within 24 hours after reconstitution.
- Reconstituted product should be stored in a refrigerator (2~8℃).
Indication and Usage
Temporary improvement of forehead lines associated with corrugator and/or procerus muscle activity in adult patients between 20 to 65 years old
Upper limb spasticity after stroke in adult patients above 18 years old
Storage
The unopened lyophilized vial should be stored in a freezer(blow -5℃) or refrigerator (2~8℃).
How supplied
Botulax is supplied in a single-use vial.
Expiration
The shelf-life of Botulax is 24 months from the manufacturing date.
Specification
Specification
| Voltage | No |
|---|---|
| Materials | No |
| Package Size(cm) | No |
| Gross Weight | 0.1KG |
| ODM&OEM | No |
Shipping&Payment
Shipping
1, Air Express (DHL/FedEx/UPS)
Delivery time: 5-7 business days.
Delivery country: over 100 countries including the USA, Canada, Australia, Chile, Ecuador, Japan, EU, etc…
Importation duty: The buyer covers importation duty depending on the destination's customs regulations.
2, Air Economy
Delivery time: For items below 2KG, it takes about 21~30 days;
Delivery country: over 100 countries including the USA, Canada, Australia, Chile, Ecuador, Japan, EU, etc.
Importation duty: iBeautyMachine.com covers importation duty.
3, Free shipping* for an order over 500 US dollars after a discount or coupon/promo code
(1) Items below 35KG
Delivery time: about 14~21 days depending on the actual situation.
Delivery method: Air Cargo shipping to the destination country, then transferred to the local courier for delivery. Usually online tracking information will be updated after 10 days.
(1) Items over 35KG
Delivery time: about 45 days depending on the actual situation.
Delivery method: Ocean shipping to the destination country, then transferred to the local courier for delivery. Usually online tracking information will be updated after 30 days.
Note: Delivery country: currently we only deliver to the USA, Canada, Australia, the UK, New Zealand. EU, Japan, South Korea, Singapore, China, Malaysia and Vietnam.
Importation duty: iBeautyMachine.com covers importation duty.
Excludes: special items such as gas or liquid.
Remote regions may cause extra for delivery to the door.
Please refresh the checkout page if you change the cart in case the free shipping option doesn't show up.
NOTE:
Warehouse working time: 9:00 am~ 6:pm (Monday to Friday; GMT+8).
Due to the complex of international shipment, there are common occasions where the lead time is substantially extended due to customs and local post office handling. The case of delay is particularly high during periods of public holidays, festive seasons, and adverse weather conditions. Please understand that we do try our best to dispatch orders as soon as they are received, and we thank you for remaining patient while your order is being delivered.
Payment
We accept payment by Credit Card, T/T(Wire Transfer), Western Union, and MoneyGram.
Please note: We DO NOT accept Credit Card payments for product value of a single unit over 1,500 USD.
If you are not happy with the order and the product, you can ask for a refund after receiving the package. Our customer support will assist you with it.
Please note: We DO NOT accept Credit Card payments for product value of a single unit over 1,500 USD.
If you are not happy with the order and the product, you can ask for a refund after receiving the package. Our customer support will assist you with it.
Taxes and Duties
We do not add taxes, VAT, or any other hidden charges. You pay us what you see on your invoice, for example, Goods Subtotal + Shipping Costs (does not include duties). Please find out as much as you can about import taxes in your own country before purchasing an item. In special cases, you may need to pay import duties on certain goods. You can contact us for further assistance on any of this.
We do not add taxes, VAT, or any other hidden charges. You pay us what you see on your invoice, for example, Goods Subtotal + Shipping Costs (does not include duties). Please find out as much as you can about import taxes in your own country before purchasing an item. In special cases, you may need to pay import duties on certain goods. You can contact us for further assistance on any of this.
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